ESPN 54th Annual Meeting

ESPN 2022


 
Impact of the body mass index on ambulatory blood pressure parameters in obese children and adolescents with normal office blood pressure
ANA KOVAčEVIć 1 INES VIDATIć 1 IVA ŠKORIć 1 BERNARDICA VALENT MORIć 1

1- SESTRE MILOSRDNICE UNIVERSITY HOSPITAL CENTER
 
Introduction:

 Our goal was to investigate the influence of the degree of obesity on ambulatory blood pressure (BP) parameters in selected group of office normotensive obese children and adolescents. This study is unique because it is the first one which included only obese office normotensive patients in order to establish if the deviation in ambulatory BP parameters ​​is proportional to the increasing body mass index (BMI).

Material and methods:

In total, 119 obese patients (55 males, 46.2%) aged 7-18 years (mean 14.22 years), divided into 3 groups based on their BMI Z-score were included in our study. They all underwent ambulatory blood pressure monitoring (ABPM).

Results:

 This study shows that obese patients, even if office normotensive, have alterations in BP values obtained by ABPM. We found a positive correlation between systolic and diastolic BP and BMI in our patients (p 0.001), however there was no correlation between this parameters on the level of different BMI subgroups. Daytime blood pressure load correlated with rising BMI and was higher in groups II and III compared to group I (p<0.001). BMI category did not influence the dipping pattern in our subjects although most of our subjects (66.4%) showed non-dipping pattern for systolic BP. The difference in BPV was confirmed only for daytime systolic and diastolic values between groups I and II (p=0.019 and p=0.002, respectively). 

 

Conclusions:

 Systolic and diastolic BP values obtained by ABPM in office normotensive obese children and adolescents are higher in subjects with higher BMI. Patients with increased BMI have increased daytime blood pressure variability and higher percentage of BP readings above 95th percentile. Obese patients show non-dipping pattern, independently on the rising BMI category. This study shows the importance of performing ABPM in obese, office normotensive patients, in order to promptly recognize individuals with higher cardiovascular risk and assure early intervention.