ESPN 54th Annual Meeting

ESPN 2022


 
EVALUATION OF BLOOD PRESSURE AND RENAL FUNCTIONS IN CHILDREN WITH COVID-19 INFECTION
ÖZGE ÖZÇELIK 1 SELMA OKTAY ERGIN 2 Medine Helin TANFER 1 Nazlı UMMAN 1 Ahmet IRDEM 2 Hasan DURSUN 3

1- Health Sciences University, Prof. Dr. Cemil Taşçıoğlu City Hospital, Department of Pediatrics
2- Health Sciences University, Prof. Dr. Cemil Taşçıoğlu City Hospital, Department of Pediatric Cardiology
3- Health Sciences University, Prof. Dr. Cemil Taşçıoğlu City Hospital, Department of Pediatric Nephrology
 
Introduction:

COVID-19 may result in pathologies such as high blood pressure and renal dysfunction. The aim of this study is to investigate the rate of hypertension and the renal damage in children who had COVID-19 infection.

Material and methods:

A total of 97 children, 61 girls and 36 boys, aged between 4-18 years, who were admitted to the Pediatric Nephrology and Pediatric Cardiology outpatient clinics with a history of COVID-19 at least 3 months ago are included in this study. A total of 22 healthy children, 13 girls and 9 boys, similar to the patient group in terms of age and gender, were included in the control group. A 24-hour ambulatory blood pressure measurement was performed in all of the cases included in the study. Blood and urinalysis results were recorded retrospectively from patient files and hospital electronic medical records.

Results:

When the patient and control groups were compared in terms of ambulatory blood pressure monitoring findings, hypertension was found in 35 (36%) of 97 patients included in the study, whereas hypertension was found in only 1 (4.5%) of 22 patients in the control group. The mean 24-hour, day and nighttime mean arterial pressure, nighttime systolic blood pressure and blood pressure load are statistically significantly higher in the group that had COVID-19 compared to the controls. In addition, 24-hour, day and nighttime heart rate, systolic and diastolic dipping are found to be statistically significantly lower in the group who had COVID-19. Statistically significant elevations were found in the group with COVID-19 infection in terms of hemoglobin, hematocrit, creatinine, and potassium.

Conclusions:

In this study, the hypertension rate of patients with COVID-19 infection is found to be higher than the control group, and it is an important finding that they are non-dipper in addition to being hypertensive. Moreover, the blood creatinine level, which is one of the biochemical parameters retrieved from the patients, is found to be higher than the controls group, suggesting that COVID-19 infection affects renal glomerular functions but not renal tubular functions.