ESPN 54th Annual Meeting

ESPN 2022


 
Illness-related Parental Stress and Quality of Life in Children with Chronic Kidney Disease: A Multi-centric Study
ELKE DE BRUYNE 1 LORE WILLEM 2 KOEN VAN HOECK 3 SARAH REYNAERT 3 SYLVIE VANKERCKHOVE 4 BRIGITTE ADAMS 4 STEPHANIE LEROI 5 LAURE COLLARD 5 ALINE MICHAUX 6 NATHALIE GODEFROID 6 DJALILA MEKAHLI 2 NOëL KNOPS 2 ELINE VAN HOECKE 1 SUNNY ELOOT 7 ANN RAES 8 EVELIEN SNAUWAERT 8 JOHAN VANDE WALLE 8 ELENA LEVTCHENKO 2

1- PEDIATRIC PSYCHOLOGY, DEPARTMENT OF PEDIATRICS, GHENT UNIVERSITY HOSPITAL, BELGIUM
2- DEPARTMENT OF CHILD NEPHROLOGY AND ORGAN TRANSPLANTATION, LEUVEN UNIVERSITY HOSPITAL, BELGIUM
3- DEPARTMENT OF PEDIATRIC NEPHROLOGY, ANTWERP UNIVERSITY HOSPITAL, BELGIUM
4- DEPARTMENT OF PEDIATRIC NEPHROLOGY, QUEEN FABIOLA CHILDRENS UNIVERSITY HOSPITAL BRUSSELS, BELGIUM
5- DEPARTMENT OF PEDIATRIC NEPHROLOGY, CHC HEALTH GROUP MONTLéGIA CLINIC,LIEGE, BELGIUM
6- DEPARTMENT OF PEDIATRIC NEPHROLOGY, SAINT-LUC BRUSSELS UNIVERSITY HOSPITAL, BELGIUM
7- DEPARTMENT OF NEPHROLOGY, GHENT UNIVERSITY HOSPITAL, BELGIUM
8- DEPARTMENT OF PEDIATRIC NEPHROLOGY & RHEUMATOLOGY, GHENT UNIVERSITY HOSPITAL, BELGIUM
 
Introduction:

Monitoring the psychological well-being of children with chronic kidney disease (CKD) is seen as standard care in pediatric nephrology, as many studies have shown that CKD has a great psychological impact. This multi-centric cross-sectional study investigated quality of life (QoL) and illness-related parental stress in this population by 1/ comparing mean levels of these two variables between several CKD categories, and 2/ exploring their correlation.

Material and methods:

We recruited children with CKD and their parents, followed at the 6 Belgian revalidation reference centers for child nephrology. Childrens QoL was assessed by the PedsQLTM 4.0 Generic Core Scales, parental stress was measured by the Pediatric Inventory for Parents (PIP). All patients were divided in categories based on their CKD diagnosis: 1/congenital diseases 2/ tubulopathies and metabolic diseases, 3/ nephrotic syndromes, 4/ acquired diseases with proteinuria and hypertension, and 5/ kidney transplantations.  

Results:

In total we included 295 children (176 boys; M age= 11.8, SD = 3.7) and 285 parents. Fifty-seven children (19%) had transplant in the past. There were no significant differences in QoL between CKD categories as reported by the children (p>.05). In contrast, there were significant differences between CKD categories in QoL (F(4, 220) = 3.46, p<.01)) and stress (F(4,269) = 2.92, p<.05), reported by parents, with transplant patients having lower QoL (t(220) = - 3.31; p = .001) and higher parental stress (t(269) = 2.30; p = .02). Finally, there were significant negative correlations (p < .001) between QoL and parental stress. 

Conclusions:

This multi-centric study showed lower levels of QoL and higher levels of parental stress in transplanted children with CKD, compared to children without transplant, when based on parent reports. More parental stress is associated with worse QoL in the child. These results highlight the importance of a multidisciplinary team with special attention for the parents.